The heart of the ISIS system is the Datastore. The ISIS Datastore is a central repository stores all customer, provider, contact, email, documentation, notes, quote requests, coverage quotes, and any other related information in a centralized database and document file. This empowers every business to access their information from any networked PC running ISIS 7. The need to "look things up" becomes obsolete.

ISIS was developed with a user-centric design to solve the problem of storing and retrieving large amounts of email, documentation and electronic data that exists in the Group Heath Insurance arena. Typical organizations try and compensate for the vast amounts of information by creating paper based files and lengthy office procedures. ISIS solves this issue by utilizing a centralized database with a document store. Each data item is stored in a central location where all users can access it. Separate copies of the item are not stored for each client, which eliminates problems with users having to ensure they are working with the most current information. Their system does not need to make sure that all copies of the data are updated with the current values, because there is only one copy in the central location.